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Renal glutathione S-transferase mu type 1 expression is already reduced in new-born spontaneously hypertensive rats

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Typically, glutathione IV therapy is administered once a week over eight to ten weeks for noticeable results

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Morroniside has several obvious advantages as a potential therapy

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It walks through key targets such as ENaC, ROMK, CLC-K, CLC-5, APOL1, NKCC2, SLC6A19, TRPCs, and TRPPs, and shows how dysfunction at the membrane level can drive severe renal phenotypes

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