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Red Blood Cell Formation: Inadequate B12 levels can lead to anemia, resulting in reduced oxygen delivery to your body's tissues, causing weakness and paleness

Time to disease progression and time to development of disease-related pain were the initial primary end points, but the primary end point was changed before unblinding based upon survival differences in two previous trials of similar design (described below).[71][Level of evidence A1] After a median follow-up of 34.1 months, the overall mortality was 61.6% in the sipuleucel-T group versus 70.8% in the placebo group (HR death, 0.78

Li C, Zhou L, Sun H, Yang MM

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