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Commonly encountered agents were summarized by proposed mechanism, evidence tier, and perioperative considerations ( Table 1 )

Furocoumarin derivatives increased the number of skin basal layer melanocytes and melanin-containing hair follicles, and upregulated melanin synthesis and TYR activity by activating cAMP/PKA and MAPK signalling pathways [268]

It is primarily used in in vitro and in vivo biochemical research to investigate tissue repair mechanisms, angiogenesis, anti-inflammatory pathways, and gastrointestinal protection