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Introduction As one of the most well-known class B1 G-protein-coupled receptors (GPCRs), the glucagon like peptide-1 receptor (GLP-1R) is a clinically validated drug target for type 2 diabetes and obesity 13

Si se extrapola lo anterior a los estudios realizados con orlistat, se puede afirmar que el uso de este frmaco, sumado a cambios en el estilo de vida, es ligeramente ms eficaz que el uso de sitagliptina por s sola en el control de la HbA1c