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Conversely, abundant iron and lipid-rich conditions in the TME favour ferroptosis induction

The most notable of these transporters in the intestine is P -glycoprotein (Pgp) or Multidrug Resistance protein 1 (MDR1)

Abstract Hypobaric hypoxia is widely recognized as a prominent risk factor for high-altitude cerebral edema (HACE), which contributes to the exacerbation of multiple pathological mechanisms, including oxidative stress, mitochondrial dysfunction, disruption of blood;brain barrier integrity, neuroinflammation, and neuronal apoptosis

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