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Recently, with the invention of microfluidic Organ Chip models of human intestine, these challenges have been overcome ( One of the earliest human gut-on-a-chip devices was developed by Kim and co-workers which was a revolutionary peristaltic, microfluidic, 2-channel Gut Chip model comprising a porous flexible membrane serving as a scaffold for intestinal epithelial cells and coated with ECM, that is sandwiched between 2 microfluidic channels

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PMID: 41480755