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Significant changes in leptin, which is regarded as a special body weight regulating hormone, were also noted (29), meaning that the resistance to leptin is partly improved in obese subjects

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In its Departmental Plan, Health Canada commits to proposing regulatory amendments to enable more innovation in drug clinical trials and make Canada a more attractive place for companies to invest. It also plans to introduce amendments aimed at improving predictability for regulated parties and streamlining authorisation processes for health products, while maintaining safety, effectiveness and quality standards.

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