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Overall, compared with the large and growing amount of pre-clinical and mechanistic evidence highlighting the reward-modulating and thus potentially anti-addictive properties of GLP-1RAs, only a few studies have investigated thus far the potential use of these medications in clinical populations with alcohol- or other substance-use disorders
Although much of the hair loss being reported after starting GLP-1 medications could be temporary telogen effluvium related to rapid weight loss or nutritional stress, he believes it is entirely plausible that in those genetically predisposed to androgenetic alopecia, [GLP-1s] may be triggering its early onset. Nusbaum, of the Miami Hair Institute, said he has started to see several patients with underlying androgenetic alopecia, which is male- or female-pattern hair loss, where that underlying condition is being exacerbated by the use of these medications. Androgenetic alopecia has a distinct pattern
Understanding the evidence, knowing who should exercise caution, and recognising when to seek medical advice are essential for informed decision-making about GLP-1 therapy
Semaglutide produces average weight loss of 10-15% of body weight
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