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Inflammatory bowel disease treatments and predictive biomarkers of therapeutic response

Substantial weight gain is also a common side effect of many mood-altering drugs (psychotropics), which include antidepressants and antipsychotics, especially for individuals with severe mental illnesses like schizophrenia and major depressive disorder who must take their medications indefinitely to reduce the risk of symptom relapse

However, these agents were linked to an increased likelihood of procedure discontinuation, presumably due to aggravated gastric retention [22]

Studied doses typically range from 900 to 1,500 mg daily, divided into two or three doses to minimize gastrointestinal side effects, though it's important to note that berberine has poor and variable oral bioavailability