does glp-1 cross the blood brain barrier This figure illustrates neuroprotective mechanisms attributed to The Multifaceted Nature of GLP-1:

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Cytosolic GSH increases because oxidative stress activates CBS and GCS increasing the flux through the GCS and GS reactions and simultaneously lowering the cytosolic cysteine concentration

A non-significant reduction in HOMA-IR at the end of 4th week during 4-week intermittent fasting might be related to insufficient accuracy of the HOMA-IR equation in our study population