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Resistance training is particularly important during weight loss to help preserve metabolic rate and functional capacity

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The first GIP receptor antagonist was introduced in 1986 ( Figure 3 ), and in recent years, the truncated and deactivated form of GIP, GIP(3-30)NH 2 , has proven to be a potent and specific GIP receptor antagonist in humans in high concentrations, and suitable for studies of endogenous GIP physiology and pathophysiology ( Table 1 )

Tirzepatide, an injectable medication for weight loss and diabetes management, is seen as a major advancement, but its affordability remains a concern