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One of its primary actions is slowing gastric emptying, which means food stays in the stomach longer after eating, helping patients feel full for extended periods

Tirzepatide is commonly discussed around GIP and GLP-1 pathway research, while Retatrutide is commonly discussed around GIP, GLP-1 and glucagon pathway research

This becomes relevant for diabetes because blocking the SGLT2, and therefore preventing that reabsorption, allows excess glucose to be excreted in the urine rather than returned to the bloodstream

Tobevibart and elebsiran are in development for the treatment of chronic hepatitis B virus (CHB) and hepatitis D virus (CHD) infections and have been shown to potently reduce HBsAg and HDV RNA