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Subsequently, RVG peptide-guided exosomes were employed to deliver short interfering RNA to neurons, microglia, and oligodendrocytes in the brain by targeting the gamma-aminobutyric acid (GABA) receptor, inducing target gene knockdown with negligible nonspecific uptake in other tissues 35

Retatrutide at the 12 mg dose produces approximately 28.7% body weight loss at 68 weeks, compared to 14.9% with semaglutide 2.4 mg at the same timepoint

doi: 10.4172/2529-797X.1000024 48 HeitmannK.NordengH.HolstL