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Obesity 33, 452462

doi: 10.1371/journal.pone.0061965

Oxidative stress assessment by immuno-fluorescence ROS levels were also assessed using the dihydroethidium (DHE) probe, according to previously published protocols [28, 29]

SURMOUNT-1 Trial: The Landmark Study The SURMOUNT-1 trial, published in The New England Journal of Medicine , studied 2,539 adults with obesity (BMI 30+) or overweight (BMI 27+) with at least one weight-related comorbidity