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This process further exacerbates oxidative damage and neuronal injury ( As a pivotal driver of neuronal damage and disease progression, OS also regulates various intracellular signaling pathways

The first extensively used agonist of GLP-1R was exendin-4, a 53% homologous peptide extracted from the venom of a Gila monster ( Heloderma suspectum ), while its potent antagonist is exendin 939

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