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A postmortem study reported reduced neural mRNA expression of the tricarboxylic acid cycle enzyme malate dehydrogenase in BD [53]

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The hormone then performs several important functions: stimulates insulin release from the pancreas reduces glucagon (which raises blood sugar) slows stomach emptying signals fullness to the brain helps stabilise blood-glucose levels after meals In simple terms, GLP-1 acts as a metabolic traffic controller , helping the body process food efficiently and preventing large spikes in blood sugar