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This ability to mitigate both cardiovascular and renal complications marks a significant advance in diabetic care, especially for patients at higher risk of these conditions

Since endocrinological changes such as changes to leptin, ghrelin, and GIP levels that promote weight regain persist long after weight loss [10], patients with obesity regain weight after one year of lifestyle modification

The study population was identified in the Danish Civil Registration system using the unique personal identification number (CPR), ensuring precise linkage of recorded individual-level information across registers [21]

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