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Metabolic effects of bile acids: potential role in bariatric surgery

Unlike hormone replacement therapy (HRT), which carries its own risk-benefit profile, GLP-1 compounds work through the appetite and metabolic regulatory system rather than replacing declining estrogen

This can affect strength and long-term balance

When faced with such a prospect, a 24-h clear liquid diet does not seem to pose an equal risk or inconvenience. The bottom line is this: the most risk-mitigating approach based on the evidence would be to have patients fast for longer (ideally no solids for 24 hours and no liquids for perhaps longer than 2 hours)