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Other activators of pancreatic beta cells Incretin hormone receptor agonists (discussed below) can reduce beta cell apoptosis in vitro and in animal models, probably via cAMP and protein kinase A (PKA) activation, and provide the best evidence-supported opportunity to preserve the beta cell population at this time

Both are FDA-recognized routes for semaglutide

Further studies should assess the appropriate dose of curcumin to achieve the greatest benefits and determine whether curcumin can enhance the effect of standard-of-care treatment in limiting OSMF disease progression

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