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Since 1800 mg NAC twice daily was very well tolerated and cohort 3 showed the greatest improvement in macular sensitivity, it has been selected as the dose for a multicenter trial aimed at determining the long-term safety of NAC and whether long-term NAC can promote cone survival in patients with RP

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Acid base reactions spontaneously proceed in a direction that gives weaker acids from stronger acids I like to call this The Principle of Acid-Base Mediocrity