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Depression and anxiety rates among PCOS patients are documented at 56.9% and 61.8% in Pakistan, respectively, which are much higher than the global average, indicating higher chances of PCOS and associated health issues [28]

Reynolds and colleagues then showed in a 2021 Nature Communications paper that MOTS-c improved running capacity in young, middle-aged, and older mice, which is why some clinic and community sources call it an exercise-mimetic