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For more information, see: Serious and Boxed Warnings The labeling for both tirzepatide and semaglutide carry Boxed Warnings , the FDAs strongest safety warning, for a possible increased risk of thyroid tumors, including cancer, which has been seen in animal studies

Considering the increasing use of GLP-1 RAs in obesity and among patients on psychotropic drugs, further research is essential to evaluate psychiatric safety in high-risk populations

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Multiple studies have also shown its efficacy in aiding weight loss efforts in overweight individuals