By delaying the movement of food from the stomach to the intestine, semaglutide can reduce the speed and amount of glucose entering the bloodstream, thereby improving glycemic control in individuals with diabetes

Contact your healthcare provider if you experience: Severe or persistent cramps that do not respond to self-care measures or significantly impact your quality of life and daily activities Frequent cramping occurring multiple times daily or nightly, disrupting sleep and functioning Associated symptoms including muscle weakness, numbness, tingling, or changes in sensation, which may suggest neurological involvement Swelling, redness, or warmth in the affected leg, which could indicate deep vein thrombosis or other vascular complications Severe gastrointestinal symptoms with signs of dehydration such as decreased urination, dizziness, confusion, or rapid heartbeat Cramps that began after starting semaglutide and persist despite adequate hydration and nutritional measures Seek immediate medical attention (call 911) if you develop: Chest pain, shortness of breath, or severe abdominal pain Signs of severe dehydration including inability to keep down fluids, minimal urine output, or altered mental status Symptoms suggesting acute kidney injury, such as significantly decreased urination, swelling, or confusion Your healthcare provider can perform a comprehensive evaluation including physical examination, review of your medication regimen, and laboratory testing to assess electrolyte levels, kidney function, and other relevant parameters

People experiencing severe GI side effects If you are in the group dealing with significant nausea, vomiting, or diarrhea, your dehydration risk is substantially higher than someone with mild or no GI symptoms
If you forget whether you already injected this week, you might take a second dose