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Tirzepatide was superior on all five key secondary endpoints

When Tirzepatide May Not Be Recommended Tirzepatide may not be suitable for individuals with: A personal or family history of medullary thyroid cancer Multiple Endocrine Neoplasia Syndrome Type 2 Pregnancy or plans for pregnancy Certain gastrointestinal disorders A thorough screening ensures that this treatment aligns with your overall health profile

Metformin protects pancreatic beta cells and reduces cardiovascular risk in people with prediabetes, while semaglutide delivers rapid, meaningful weight loss and improves heart health markers