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The clinical importance of this is that a small change in dose can result in a disproportionally large increase in serum concentrations, potentially leading to toxicity

Thus, a folate deficiency may elevate blood homocysteine levels, potentially causing a condition known as hyperhomocysteinemia

We also demonstrate here that mGIPR-Ab/GLP-1 peptideantibody conjugates activate c-Fos in downstream brain regions, such as the nucleus of the solitary tract, parabrachial nucleus and central amygdalar nucleus