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The most notable known mechanisms [for weight loss] are linked with the central and peripheral nervous systems through direct activation of the hypothalamus and hindbrain or indirect activation via the vagus nerve, resulting in reduced appetite and food intake

Many patients report changes within 4-8 weeks, with continued improvement over several months

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Unlike full-length hGH, AOD-9604 does not bind the growth hormone receptor and has shown no measurable effect on IGF-1 levels, glucose homeostasis, or somatic growth in the published preclinical literature