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Unlike traditional PDE5 inhibitors which act on the vascular system, PT-141 is investigated for its mechanism of action within the Central Nervous System (CNS)

In preclinical and in vitro research, Glutathione is used to investigate antioxidant defense and reactive-oxygen-species scavenging, detoxification and xenobiotic metabolism, redox signaling via the GSH/GSSG ratio, immune-cell function, neuroprotection, and hepatic and age-related research

Beyond its primary use, Viagra has also been studied for its potential benefits in treating other conditions, such as pulmonary arterial hypertension, due to its effects on blood flow