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However, its impact on the gastrointestinal system brings to light a less favorable aspect of treatment: the occurrence of heartburn among some patients

However, clinical practitioners often recommend a "start low and go slow" approach, particularly for patients with severe chronic illness who may be highly sensitive to new supplements or prone to detoxification reactions (Herxheimer reactions)

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When patients express interest in combining these substances, clinicians should conduct a thorough assessment including medical history, current medications, baseline kidney function, and treatment goals