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Clinical and real-world evidence have demonstrated the potential of GLP-1RAs to reduce the risk of all-cause dementia and dementia due to AD in people with T2D [32, 34,35,36], and liraglutide has been shown to reduce neurodegeneration and the speed of decline in cognitive function in people with AD [29, 30]

Patients are randomized to pemvidutide 1.2 or 1.8 mg weekly, or placebo for 24 weeks, with primary endpoints of MASH resolution without fibrosis progression and fibrosis amelioration without MASH deterioration

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However, the GLP-1 hormone has a very short half life, meaning it doesnt last very long in your system