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Summary: GLP-1 receptor agonists do not directly cause irregular periods, but the significant weight loss they produce can temporarily affect menstrual regularity through metabolic and hormonal changes

Careful monitoring and a lower threshold for checking B6 levels is appropriate in this population

Genomewide association study of statin-induced myopathy in patients recruited using the UK clinical practice research datalink

Overall, existing inhibitors suffer from insufficient selectivity, highlighting the urgent need for LONP1-specific agents developed through advanced approaches such as cryo-electron microscopy and molecular dynamics simulations to expand therapeutic options