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A patient with untreated insulin resistance will have a diminished response to CJC-1295/Ipamorelin because their GH signaling pathway is already compromised

doi: 10.1186/1758-5996-5-57 3 SaeediPPetersohnISalpeaPMalandaBKarurangaSUnwinNet al

The etiology primarily lies beside the abnormal skin cell proliferation facilitated by the unrepaired DNA of skin cells which owes to DNA mutations or genetic defects