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Extracellular vesicles from the inflammatory microenvironment regulate the osteogenic and odontogenic differentiation of periodontal ligament stem cells by miR-758-5p/LMBR1/BMP2/4 axis
Introduction Glucagon-like peptide-1 receptor agonists (GLP-1RA) are effective therapies for patients with type 2 diabetes (T2D) and/or obesity, particularly for those with coexisting cardiovascular disease and/or high cardiovascular risk [1]
In a dose ranging study, weekly injection of albiglutide effectively and stably reduced fasting plasma glucose and HbA1c levels with less frequent nausea and vomiting compared to biweekly or monthly injection of albiglutide or twice daily exenatide injection [71]
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