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Applying inclusion and exclusion criteria for the selection of relevant articles, reaching the conclusion that the long-term use of semaglutide produces effects on body weight and modification of cardiovascular risk factors, which is associated with a reduction in the premature mortality rate and improvement of the complications associated with having an elevated body mass index

[13] The FDA also considered data from one separate trial (NCT01720446 [74] ), which was sponsored by Novo Nordisk, of 3297 participants with type 2 diabetes who were at high risk for cardiovascular events

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