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Description

Animal Model:Naturally aged male C57BL/6 mice (20-24 months old) [1] Dosage:5 mg/kg Administration:Intraperitoneal injection, every other day for three administrations Result:Increased serum testosterone levels

C 1 was then used to drive the distribution of 7,8-DHF to the brain using a physiologically based PK model with perfusion-limited distribution (Figure 1)