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Schusdziarra, V., Zimmermann, J.-P., Erdmann, J., Bader, U

PMID: 10469335[PubMed Reference] Philp D, Badamchian M, Scheremeta B, et al

68:115-123 [PubMed: 25173606] 124

As a transcription target of p53, the activity of spermidine/spermine N 1 -acetyltransferase 1 (SAT1), the rate-limiting enzyme in polyamine catabolism, induces lipid peroxidation and sensitizes cells to undergo ferroptosis and the deletion of SAT1 suppresses p53 and p53 3 KR -mediated ferroptosis