Most people see a 50% or greater reduction within 3 to 5 days of strict elimination
Because of this, its plausible that some patients could experience broader systemic effects, including hormonal or temperature-related symptoms
While GSH is essential for inhibiting ferroptosis by neutralizing ROS, CHAC1 degrades GSH, reducing the cells capacity to prevent oxidative damage
1: Investigations of our patient MCV: Mean corpuscular volume, MCH: Mean corpuscular hemoglobin, WBC: White blood cell, TSH: Thyroid stimulating hormone, LDH: Lactate dehydrogenase, DCT: Direct Coombs test, ANA: Anti-nuclear antibody, IF: Intrinsic factor, NCS: Nerve conduction study, SACD: Subacute combined degeneration of the spinal cord Fig