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[60] identified phospholipid-modifying enzymes Lysophospholipid acyltransferase 1 (also known as MBOAT1) and Lysophospholipid acyltransferase 2 (also known as MBOAT2) as ferroptosis suppressors through a whole-genome CRISPR activation screen

Cellular senescence: from physiology to pathology

ATF4 activation upregulates GSH and dTTP pools in T315I-Bcr-Abl-32D cells Next, we want to address the questions of what causes the increases in dTTP and GSH biosynthesis in T315I-Bcr-Abl and whether blocking the upregulation of these two factors can increase JMF4073 sensitivity

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