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These are signs of bacterial contamination or peptide degradation

Patients should not discontinue tirzepatide without medical guidance, except in cases of suspected severe allergic reactions or pancreatitis, where holding the medication pending urgent evaluation is appropriate

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The same investigators conducted a similar study in individuals with type 2 diabetes but here they found a modest effect of allulose on glycemic control while insulin levels remained unaffected (Reference Braunstein, Jarvis and Noronha36)