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Valdez-Taubas, J

Many peptide systems discussed herein have been repeatedly shown to exert robust physiological effects in vivo , often across multiple species, yet lack approved therapeutic analogs or advanced clinical programs despite decades of investigation

Lees studies are smaller than most rigorous clinical trials, ranging in size from two to 16 study participants, and dont include comparison groups

Genes downregulated by copper peptide ghk-cu include those linked with swelling (pro-swelling cytokines, swelling signaling), fibrosis and scarring (TGF-beta pathway components), cancer progression (oncogenes, metastasis-related genes), and tissue breakdown (certain proteases)