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These include exogenous and endogenous compounds, dietary manipulations, modulation of metabolic pathways, stem cell approaches, and cell signaling processes [10,11,14,15,16,17,18,19,20,21]

(6) Meta-analyses: A systematic review & meta-analysis found that in autistic children with cerebral folate deficiency or folate receptor alpha autoantibodies, treatment with folinic acid (leucovorin) was associated with improvements in communication, irritability, and other core symptoms