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World J Biopharm Sci

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Statins inhibit HMG-CoA reductase, decreasing ergosterol synthesis and impairing biofilms in Candida , Aspergillus , and zygomycetes, often synergizing with fluconazole (Macreadie et al., 2006

These patients also exhibit polymorphisms to the serotonin receptor 2A region of chromosome 13 and the human leukocyte antigen region of chromosome 6, as well as abnormalities in catechol- O -methyltransferase