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Only the essentials for the day: Water (23 liters) Snacks (dried fruit, chocolate, cookies) Camera or phone Extra jacket, hat, gloves Personal documents Trekking poles (recommended) Everything else (tents, food, sleeping bag) is carried by the pack horses

Biol Pharm Bull 39(2):199206 Shen C, Li Q, Zhang YC, Ma G, Feng Y, Zhu Q et al (2010) Advanced glycation endproducts increase EPC apoptosis and decrease nitric oxide release via MAPK pathways

That sudden, sharp pain in your chest can be terrifying