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Improvements continued over six months, with many participants achieving abstinence from binge episodes altogether

C32 and C88 in PfGrx) could not only form an intramolecular disulfide during catalysis or affect the reactivity of the active-site thiolate but also function as a resolving cysteine for trapped Grx(SSR) species (Fig

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The suggested mechanism could be the deactivation of hydroperoxide through the reversion of riboflavin from the reduced form (dihydroriboflavin) to the oxidised form (Fig