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This is because modulators of addictive behavior are limited and we lack a comprehensive understanding of their mechanisms

Even without a medical need for weight loss, we can work with patients toward an informed approach that respects their bodily autonomy and recognizes their societal discord and experiences living in larger bodies

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Available from: Accessed: 19 Sep 2025 Frias JP, Hsia S, Eyde S et al (2023) Efficacy and safety of oral orforglipron in patients with type 2 diabetes: a multicentre, randomised, dose-response, phase 2 study