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As a result of the action of these substances, the cells became more susceptible to BCL-2 family inhibitors, especially the compound ABT-263, which has proven senolytic properties [135]

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The REDEFINE 2 trial in patients with type 2 diabetes showed CagriSema achieved HbA1c levels of 6.5% or below in 73.5% of participants

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In aged animals, it achieved a rather impressive effect by clearing senescent cell rates by 50-70% without affecting healthy dividing cells

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Cellular redox balance and oxidative stress mechanism research

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