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Importantly, some drugs such as proteins and peptides are inappropriate for oral administration because they are significantly degraded by gastric acid and proteolytic enzymes in the gastrointestinal (GI) tract, and rapidly metabolized by the first-pass effect in the liver

All these changes lead to cytokine storm characterized by increased expression and release of proinflammatory cytokines that participate in the pathogenesis of ARDS during virus respiratory infections like COVID-19

Bake for 25-30 minutes or until meatballs are a deep golden brown and the inside is cooked through