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In addition, our analysis demonstrated significant variability in RORs for GLP-1 RA-related NAEs across agents, with semaglutide exhibiting stronger disproportionality signals compared to lixisenatide and tirzepatide
Three percent of participants in the drugs pivotal trial reported hair loss (three times as many as those who used a placebo)
August 9th, 2025: Novo Nordisk Increases Trademark Lawsuits Over Compounded Ozempic Products Novo Nordisk has intensified its legal campaign to protect the Ozempic trademark, filing 14 additional federal lawsuits against pharmacies, telehealth providers, and other sellers marketing compounded semaglutide products
According to NICE guideline NG28, GLP-1 receptor agonists should be considered when: Triple therapy (metformin and two other oral drugs) is not effective, not tolerated, or contraindicated The patient has a BMI 35 kg/m (or lower in people of Black, Asian and other minority ethnic groups) and specific obesity-related comorbidities The patient has a BMI 40% reduction in non-HDL cholesterol GLP-1 receptor agonist for glycaemic control and weight management (with secondary lipid benefits) Ezetimibe if non-HDL cholesterol reduction is insufficient Lifestyle interventions addressing diet, exercise, and weight Monitoring and follow-up are essential components of cholesterol management
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