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Similarly, ICV pretreatment or peripheral post-treatment with the DEETGE-Cal-Tat peptide was also able to decrease Keap1-Nrf2 interaction in the rat hippocampal CA1 region after global cerebral ischemia (GCI) and, as a consequence, to induce Nrf2 target genes and a powerful neuroprotection of hippocampal-dependent cognitive function after GCI [302]

Additionally, the use of molecular docking and in silico methods to better predict the interaction between phytochemicals and cancer targets could help in designing nanoparticles with enhanced therapeutic efficacy and specificity (186)

This new option has been welcomed in the fight against obesity in the U.S

If home monitoring reveals persistent hyperglycaemia despite GLP-1 therapy, contact your healthcare provider for medication adjustment