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Since it is compounded, formulations vary by compounding pharmacy and prescriber order, which further shapes how a weekly plan is built

Osteocytes secrete sclerostin in response to mechanical stress, which acts on the Wnt/-catenin pathway in osteoblasts to inhibit cell proliferation, impair mineralization, enhance apoptosis, and promote osteoclast formation and activity in a RANKL (receptor activator of nuclear factor B (NF-B) ligand)-dependent manner (Horwood, 2016)

La modificacin "LR3" sustituye el cido glutmico por una arginina en la posicin 3 y extiende la cadena de aminocidos