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Gastrointestinal issues that are common with semaglutide may increase a persons risk of developing deep vein thrombosis

While berberine is a powerful supplement with real metabolic benefits, it is not a direct substitute for a GLP-1 agonist

Effect of the glucagon-like peptide-1 receptor agonist liraglutide, compared to caloric restriction, on appetite, dietary intake, body fat distribution and cardiometabolic biomarkers: a randomized trial in adults with obesity and prediabetes

So your prescriber can help match you with the option that best fits your needs: Ozempic: Approved for Type 2 diabetes and to lower the risk of serious cardiovascular and kidney-related problems in certain people Wegovy: Approved for weight loss and to lower the risk of serious cardiovascular problems if you have heart disease and a larger body size Mounjaro:Approved for Type 2 diabetes Zepbound: Approved for weight loss and moderate-to-severe obstructive sleep apnea (OSA) Be prepared to share details about your current compounded GLP-1 prescription